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Transmucosal Glucose: What It Is and Why It Matters

  • Writer: Lizzie Luh
    Lizzie Luh
  • Aug 19
  • 2 min read

Updated: Sep 2

When you’re managing hypoglycemia, timing is everything. That’s why transmucosal glucose—glucose absorbed through the mouth's membranes—has become an important option for people who need fast-acting support. At Rally Higher, we chose this delivery method for a reason: it’s designed to be quick, low-effort, and reliable in the moments that matter most.


What Is Transmucosal Glucose?

Transmucosal glucose refers to glucose that dissolves and absorbs through the tissue in the mouth. This area is rich in blood vessels, which allows certain ingredients to bypass digestion and enter the bloodstream more directly.

This makes transmucosal delivery especially helpful when someone is experiencing symptoms like shakiness, confusion, or nausea—moments when chewing or swallowing may be difficult.


How Transmucosal Absorption Works

Unlike tablets, gels, or sugary drinks, which pass through the digestive system before raising blood sugar, transmucosal glucose dissolves in the mouth and begins absorbing through the mucosal lining. This route may allow for quicker uptake—because it doesn’t rely on the stomach or intestines to process it first.

The result? A simpler and potentially faster way to support glucose levels when you’re feeling a low come on.


How It Compares to Other Methods

Here’s how transmucosal glucose stands apart from traditional options:


Method

Requires Chewing or Drinking

Relies on Digestion

Made for On-the-Go Use

Chewable Tablets

Yes

Yes

Sometimes

Glucose Gel

Yes

Yes

Somewhat

Juice/Food

Yes

Yes

Not Always

Transmucosal Glucose

No

No

Yes

Tablets can be hard to chew during a low. Gels may be messy. Juice isn’t always on hand. Transmucosal glucose offers a portable, no-fuss alternative designed for real-life use.


Why Rally Chose Transmucosal Glucose

We designed Rally Glucose Melts with input from people who live with diabetes every day. Many shared that current options were either hard to use in the moment or didn’t act as quickly as they needed. Others said they wanted something cleaner—without artificial dyes, fillers, or bulky packaging.


Rally is different. Our glucose melts are:

  • Fast-dissolving

  • Portable and discreet

  • Made with clean-label ingredients

  • No chewing or water required


In short, we created Rally to be a tool that works when others don’t.


Why It Matters

Low blood sugar can feel overwhelming. It can interfere with daily life, workouts, sleep, and even safety. In those moments, having a glucose option that doesn’t require a lot of effort—or waiting—can make a real difference.


Transmucosal glucose isn’t just a new format. It’s a smarter, more accessible way to respond to the physical and emotional intensity of a low.


Want to be among the first to try Rally? Sign up for launch updates and early access to our January Kickstarter campaign. Join the list today.

sublingual glucose

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